What does Prodentis treat?
BioGaia Prodentis lozenges is a probiotic for healthier gum and teeth.
Two unique strains with complementary effects.
L. reuteri ATCC PTA 5289
• Human oral strain specifically selected for its ability to reduce inflammation by inhibiting TNF-α
L. reuteri DSM 17938
• Human strain selected for its efficient production of the antimicrobial substance reuterin
Lozenges come with a refreshing peppermint flavour and provides the recommended dose of 200-400 million active health-promoting L. reuteri Prodentis bacteria. This regimen helps to reduce the number of periodontal pathogens and cariogens, thereby improving oral health balance.
BioGaia’s probiotic products with Limosilactobacillus reuteri (L. reuteri) is the world’s most studied probiotic for oral health. L. reuteri Prodentis® is of human origin and one of the few bacterial species that has co-evolved with humans since the beginning of time.
Why Prodentis?
BioGaia Prodentis is special!
It provides a balanced oral microbiota and as an adjunct for oral health and prevention of:
• Gingivitis
• Periodontitis
• Plaque
• Peri-Implantitis
• Halitosis (bad breath)
• Oral Candida
• Caries
Studies have shown that the results of SRP can be significantly improved with the concurrent use of BioGaia Prodentis. In addition, the beneficial effects of professional cleaning are maintained longer.
Professional mechanical cleaning
(Scaling and Root Planing: SRP)
The dental hygienist thoroughly cleans the teeth and removes tartar deposits above and below the gum line in order to reduce inflammation and pocket depth. Severe periodontitis cases may require surgical prodecures to clean the teeth and remove infected tissues.
Adjunctive therapy:
SRP with BioGaia Prodentis
A balanced oral microflora is vital for healthy teeth and gums. The oral cavity contains around 800 different species of bacteria and there are more than 1 billion bacteria on each tooth. Under normal conditions, these are in balance and protect you from illness, but in case of inflammatory periodontal disease, such as gingivitis and periodontitis, an imbalance has arisen.
SRP alone cannot remove all the “bad” pathgenic bacteria that causes gum diseases. SRP reduces the amount of bacteria, but only temporarily since the pathogens quickly recolonize the treated areas of the oral cavity.
How BioGaia Prodentis works?
Ideal properties of a probiotic intended for use in disorder of the mouth
“By taking Prodentis daily it may be possible to restore the good and natural balance in the mouth and recreate the healthy ecology”.
Clinically Proven
Clinical studies with L. reuteri Prodentis (Limosilactobacillus reuteri DSM 17938 and ATCC PTA 5289) have been shown to reduce gingival inflammation and chronic periodontitis in healthy adults.
85% less bleeding after two weeks
42 healthy adults with moderate gingivitis were randomly assigned to one of the following treatments for two weeks: one L. reuteri Prodentis lozenge per day, two L. reuteri Prodentis lozenge per day, or a placebo. L. reuteri Prodentis lozenge was shown to reduce bleeding and inflammation by 85% after two weeks of supplementation compared to placebo. The patients were followed up after four weeks.
Reduced inflammation of the gums
A clinical trial in 72 adults showed significant improvement in bleeding on probing after 6 weeks of daily supplementation with two lozenges of L. reuteri Prodentis.
Compared to baseline, bleeding on probing was reduced by 30% with L. reuteri Prodentis, while it was increased by 5% in the placebo group. The effect was achieved without any professional cleaning of the teeth or instructions regarding oral hygiene routines.
47% fewer tooth surfaces need surgery
After professional cleaning patients were given either two lozenges per day of L. reuteri Prodentis or placebo for 12 weeks. The effects on pocket depth reduction and attachment gain were significantly better with L. reuteri Prodentis compared to placebo. Compared to placebo the number of tooth surfaces in need of surgery was reduced 47% in patients with deep pockets and supplemented by L. reuteri Prodentis. The study was double-blind, placebo-controlled and included 30 patients with chronic periodontitis.
| Gingivitis | L. reuteri Prodentis reduced bleeding on probing by 85% |
| Periodontitis |
Significant reduction of pocket depth in moderate and deep pockets 47% fewer deep pocket sites in need of surgery with L. reuteri Prodentis compared to placebo Up to 90% reduction of pathogens with L. reuteri Prodentis |
| Peri-Implantitis | L. reuteri Prodentis significantly reduction of bleeding on probing and probing pocket depth in implants with peri-implantitis |
| Halitosis | L. reuteri Prodentis reduces oral malodour/bad breath |
| Oral Candida | L. reuteri Prodentis reduced the prevalence of oral Candida by more than 50% compared to placebo |
| Caries | L. reuteri Prodentis is effective in reducing caries-associated Streptococcus mutans (S. mutans) in children |
Gingivitis affects between 40 and 90% of all pregnant women from the second to the eighth month of pregnancy.
Oral health changes during pregnancy
During pregnancy the entire female body goes through changes and this also applies to the oral health. Due to the hormonal and immunological changes, a shift in the oral microbiome often leads to a decline in the oral health status.
If not taken care of, the imbalance can lead to dental caries, gingivitis, and periodontitis.
Pregnancy gingivitis may affect the child
Ongoing research is investigating whether there is a connection between the mother’s oral health and the health of the child. Studies have suggested that women with pregnancy gingivitis may be more likely to deliver babies prematurely or with a lower birth weight than mothers with healthy gums.
However, there are many other factors that can affect the health of a pregnant woman and her child, such as smoking, lifestyle and age.
L. reuteri Prodentis reduces pregnancy gingivitis
A double-blind, randomized, placebo-controlled study on pregnant women with gingivitis showed that supplementation of L. reuteri Prodentis significantly reduces inflammation and plaque compared to placebo.
Safety
BioGaia Prodentis is safe because:
• It is clinically documented in more than 70 studies
• It contains the bacterium L. reuteri Prodentis, which occurs naturally in humans
• It is suitable for 3 years old and above
• It can be used for long periods
• It does not stain teeth
• It does not irritate the oral mucosa
• It can also be taken during pregnancy
• It does not lower the pH of your mouth
A balanced microora is essential for a healthy gum and teeth.
Start your day with Prodentis
Simply let Prodentis melt in your mouth after ossing & brushing or when it’s convenient for you.
Take 1 or 2 lozenges a day after brushing.
Suitable for 3 years old onwards, adult, the elderly and pregnant women.